{"id":2187,"date":"2022-12-02T16:31:22","date_gmt":"2022-12-02T16:31:22","guid":{"rendered":"https:\/\/delbertpharma.com\/?p=2187"},"modified":"2024-10-04T14:18:21","modified_gmt":"2024-10-04T14:18:21","slug":"article-le-monde-delbert-sauveteur-de-medicaments-en-detresse","status":"publish","type":"post","link":"https:\/\/delbertpharma.com\/fr\/article-le-monde-delbert-sauveteur-de-medicaments-en-detresse\/","title":{"rendered":"Article Le Monde: Delbert, sauveteur de m\u00e9dicaments en d\u00e9tresse"},"content":{"rendered":"

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Article paru sur Lemonde.fr, 2 d\u00e9cembre 2022<\/h2>\n

Depuis 2013, le laboratoire pharmaceutique se bat pour redonner vie \u00e0 de vieilles mol\u00e9cules essentielles menac\u00e9es de dispara\u00eetre de l’arsenal th\u00e9rapeutique. A chaque nouveau dossier qui atterrit sur son bureau, la r\u00e8gle est toujours la m\u00eame.<\/em><\/p>\n

\u00ab Nous v\u00e9rifions que le m\u00e9dicament r\u00e9pond \u00e0 un besoin m\u00e9dical \u00e9vident, puis nous \u00e9valuons si son d\u00e9veloppement est techniquement possible en France ou en Europe. Si on est s\u00fbrs \u00e0 85 %, on fonce \u00bb , d\u00e9taille Thierry Hoffmann, directeur g\u00e9n\u00e9ral des Laboratoires Delbert.\u00a0<\/span><\/em><\/p>\n

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LIRE LA SUITE SUR lemonde.fr<\/a><\/strong><\/p>\n

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Article paru sur Lemonde.fr, 2 d\u00e9cembre 2022 Depuis 2013, le laboratoire pharmaceutique se bat pour redonner vie \u00e0 de vieilles mol\u00e9cules essentielles menac\u00e9es de dispara\u00eetre de l’arsenal th\u00e9rapeutique. A chaque nouveau dossier qui atterrit sur son bureau, la r\u00e8gle est toujours la m\u00eame. \u00ab Nous v\u00e9rifions que le m\u00e9dicament r\u00e9pond \u00e0 un besoin m\u00e9dical \u00e9vident, […]<\/p>\n","protected":false},"author":1,"featured_media":2411,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"

Article paru sur Lemonde.fr, 2 d\u00e9cembre 2022<\/h2>\r\nDepuis 2013, le laboratoire pharmaceutique se bat pour redonner vie \u00e0 de vieilles mol\u00e9cules essentielles menac\u00e9es de dispara\u00eetre de l'arsenal th\u00e9rapeutique. A chaque nouveau dossier qui atterrit sur son bureau, la r\u00e8gle est toujours la m\u00eame.\r\n\r\n\u00ab Nous v\u00e9rifions que le m\u00e9dicament r\u00e9pond \u00e0 un besoin m\u00e9dical \u00e9vident, puis nous \u00e9valuons si son d\u00e9veloppement est techniquement possible en France ou en Europe. Si on est s\u00fbrs \u00e0 85 %, on fonce \u00bb<\/em> , d\u00e9taille Thierry Hoffmann, directeur g\u00e9n\u00e9ral des laboratoires Delbert.\r\n\r\nDepuis neuf ans, cette discr\u00e8te entreprise pharmaceutique, install\u00e9e \u00e0 Paris, vole au secours des vieux m\u00e9dicaments essentiels menac\u00e9s de disparition. \u00ab En neuf ans, nous avons redonn\u00e9 vie \u00e0 une quinzaine d'entre eux. C'est une belle r\u00e9ussite \u00bb<\/em> , poursuit-il avec fiert\u00e9.\r\n\r\nTout commence en 2013, lorsque Thierry Hoffmann, pharmacien dans l'industrie, et Marc Childs, m\u00e9decin psychiatre, cassent leur tirelire pour racheter les laboratoires Delbert. \u00ab Au cours de notre parcours professionnel, nous avions \u00e9t\u00e9 choqu\u00e9s de voir de grands laboratoires pharmaceutiques abandonner de vieux m\u00e9dicaments, pourtant encore tr\u00e8s efficaces et indispensables \u00e0 certains patients, parce qu'ils n'\u00e9taient plus suffisamment rentables ou \u00e0 cause de difficult\u00e9s de production<\/em> \u00bb , raconte M. Hoffmann. Le duo se fixe alors un d\u00e9fi : racheter ces vieux m\u00e9dicaments aux Big Pharma afin de leur donner un second souffle.\r\nDans la foul\u00e9e, les deux associ\u00e9s commencent \u00e0 dresser une liste de produits en p\u00e9ril, o\u00f9 ils recensent m\u00e9ticuleusement les m\u00e9dicaments essentiels r\u00e9guli\u00e8rement en rupture de stock ou en arr\u00eat de commercialisation. Souverainet\u00e9 sanitaire.\r\n\r\nEn 2014, ils se lancent dans leur premier sauvetage en acqu\u00e9rant aupr\u00e8s de l'am\u00e9ricain Abbott le Vercyte, un traitement contre la maladie de Vaquez (\u00e0 cause de laquelle le patient produit trop de globules rouges), prescrit lorsque le traitement de r\u00e9f\u00e9rence ne fonctionne pas, et pour lequel aucune autre solution n'existe. \u00ab Le fournisseur de la mati\u00e8re premi\u00e8re avait d\u00e9cid\u00e9 d'arr\u00eater sa production pour des raisons financi\u00e8res. A l'\u00e9poque, 2 000 patients fran\u00e7ais \u00e9taient trait\u00e9s avec ce produit et risquaient de mourir s'il disparaissait<\/em> \u00bb , observe M. Hoffmann.\r\n\r\nLes \u00e9quipes de Delbert s'attellent alors \u00e0 red\u00e9velopper enti\u00e8rement le produit de A \u00e0 Z, de la synth\u00e8se du principe actif \u00e0 la fabrication du produit fini. La t\u00e2che n'est pas ais\u00e9e, car la mol\u00e9cule du Vercyte, le pipobroman, est un d\u00e9riv\u00e9 de gaz de combat que peu d'industriels ont la capacit\u00e9 de manipuler. A cette difficult\u00e9 s'ajoute une autre contrainte que s'est impos\u00e9e le laboratoire \u00e0 son lancement : relocaliser autant que possible les productions de m\u00e9dicaments sur le sol tricolore ou europ\u00e9en pour garantir une souverainet\u00e9 sanitaire. Malgr\u00e9 tout, le laboratoire parvient \u00e0 trouver un expert de la chimie fine dans l'Hexagone, puis fait appel au fa\u00e7onnier Delpharm, \u00e0 Lille, pour la production du produit fini. \u00ab Ces vieux produits sont vendus \u00e0 des prix tr\u00e8s faibles, ce qui explique que beaucoup d'industriels les d\u00e9laissent<\/em> \u00bb Thierry Hoffmann, directeur g\u00e9n\u00e9ral des laboratoires Delbert.\r\nEncourag\u00e9 par ce premier succ\u00e8s, le laboratoire parisien r\u00e9plique la formule et multiplie les rachats de produits. En 2015, il r\u00e9cup\u00e8re ainsi aupr\u00e8s de Sanofi l'Extencilline, un antibiotique qui permet de soigner la syphilis en une seule injection, et dont les p\u00e9nuries r\u00e9currentes inqui\u00e8tent alors les professionnels de sant\u00e9. \u00ab Nous sommes aujourd'hui le seul producteur en Europe de ce traitement<\/em> \u00bb , souligne M. Hoffmann. La r\u00e9putation de \u00ab r\u00e9animateur de m\u00e9dicament \u00bb du laboratoire s'\u00e9tend. Au point que l'agence sanitaire belge, alarm\u00e9e apr\u00e8s l'annonce, par son unique fournisseur, de l'arr\u00eat de la commercialisation d'amoxicilline injectable, le sollicite pour en relancer la production.\r\n\r\nCes efforts ont toutefois un co\u00fbt. Le laboratoire d\u00e9pense en moyenne un million d'euros pour revoir le d\u00e9veloppement d'un m\u00e9dicament. \u00ab Or, ces vieux produits, contrairement aux innovations, sont vendus \u00e0 des prix tr\u00e8s faibles, ce qui explique que beaucoup d'industriels les d\u00e9laissent. Ils constituent pourtant 90 % de l'arsenal th\u00e9rapeutique du m\u00e9decin \u00bb , regrette M. Hoffmann. Le laboratoire en a fait lui-m\u00eame l'exp\u00e9rience. Il a d\u00fb renoncer \u00e0 commercialiser dans les officines de ville fran\u00e7aises son amoxicilline injectable, faute de rentabilit\u00e9. \u00ab Le prix de vente en pharmacie \u00e9tait fix\u00e9 \u00e0 1,09 euro alors que le co\u00fbt de production nous revient \u00e0 1,10 euro. C'est ubuesque \u00bb , d\u00e9plore-t-il.\r\n\r\nLe laboratoire fran\u00e7ais, qui produit 90 % de ses principes actifs sur le sol europ\u00e9en, ne m\u00e9nage pourtant pas sa peine. Pour r\u00e9duire les d\u00e9penses, il fait notamment l'impasse sur la promotion de ses produits, misant sur leur notori\u00e9t\u00e9 acquise de longue date, et r\u00e9duit ses marges sur les ventes. Un mod\u00e8le \u00e0 contre-courant de celui des Big Pharma, mais qui r\u00e9ussit \u00e0 Delbert. En forte croissance, le laboratoire pr\u00e9voit de r\u00e9aliser 33 millions d'euros de chiffre d'affaires en 2022.","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"categories":[13],"tags":[],"class_list":["post-2187","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-non-classifiee"],"yoast_head":"\nArticle Le Monde: Delbert, sauveteur de m\u00e9dicaments en d\u00e9tresse - delbertpharma.com<\/title>\n<meta name=\"description\" content=\"delbertpharma.com laboratoires pharmaceutique fran\u00e7ais \u0153uvrant pour la sauvegarde de m\u00e9dicaments essentiels dans les domaines de l'infectiologie, pneumologie, oncologie, h\u00e9matologie, le syst\u00e8me nerveux central\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/delbertpharma.com\/article-le-monde-delbert-sauveteur-de-medicaments-en-detresse\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Article Le Monde: Delbert, sauveteur de m\u00e9dicaments en d\u00e9tresse - 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